FGFs/FGFRs-dependent signalling in regulation of steroid hormone receptors – implications for therapy of luminal breast cancer
Abstract Stromal stimuli mediated by growth factor receptors, leading to ligand-independent activation of steroid hormone receptors, have long been implicated in development of breast cancer resistance to endocrine therapy. Mutations in fibroblast growth factor receptor (FGFR) genes have been associ...
Main Authors: | Dominika Piasecka, Marcin Braun, Kamila Kitowska, Kamil Mieczkowski, Radzislaw Kordek, Rafal Sadej, Hanna Romanska |
---|---|
Format: | Article |
Language: | English |
Published: |
BMC
2019-05-01
|
Series: | Journal of Experimental & Clinical Cancer Research |
Subjects: | |
Online Access: | http://link.springer.com/article/10.1186/s13046-019-1236-6 |
Similar Items
-
Immunohistochemical evaluation of estrogen and progesterone receptors in peripheral and central giant cell granuloma of the jaws
by: Razavi SM, et al.
Published: (2006-07-01) -
The Role of Steroid Hormone Receptors in Urothelial Tumorigenesis
by: Hiroki Ide, et al.
Published: (2020-08-01) -
The value of the expression of endometrial receptors for steroid hormones in patients with endometriosis
by: N. Yu. Pedachenko, et al.
Published: (2020-05-01) -
Clinical association of progesterone receptor isoform A with breast cancer metastasis consistent with its unique mechanistic role in preclinical models
by: Rayna Rosati, et al.
Published: (2020-06-01) -
Distribution of estrogen and progesterone receptors in the primate ovary, with emphasis on subpopulations of cells within the corpus luteum.
by: Hild-Petito, Sheri Ann.
Published: (1988)