Infiltration of alternatively activated macrophages in cancer tissue is associated with MDSC and Th2 polarization in patients with esophageal cancer.

Myeloid derived suppressor cells (MDSCs) expand in cancer bearing hosts and contribute to tumor immune evasion. M2 macrophages constitute a major cellular component of cancer-related inflammation. However, the correlation between circulating MDSCs and infiltrating M2 macrophages in tumor tissues fro...

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Bibliographic Details
Main Authors: Jingjing Gao, Yumin Wu, Zhaoliang Su, Prince Amoah Barnie, Zhijun Jiao, Qingli Bie, Liwei Lu, Shengjun Wang, Huaxi Xu
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4140683?pdf=render