Extracellular ATP Regulates CD73 and ABCC6 Expression in HepG2 Cells

The ATP-binding cassette sub-family C member 6 transporter (ABCC6) is an ATP dependent transporter mainly found in the basolateral plasma membrane of hepatic and kidney cells. Mutations in ABCC6 gene were associated to the Pseudoxanthoma elasticum (PXE), an autosomal recessive disease characterized...

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Bibliographic Details
Main Authors: Fabio Martinelli, Flavia Cuviello, Maria C. Pace, Maria F. Armentano, Rocchina Miglionico, Angela Ostuni, Faustino Bisaccia
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-08-01
Series:Frontiers in Molecular Biosciences
Subjects:
Online Access:https://www.frontiersin.org/article/10.3389/fmolb.2018.00075/full