Identification of cis-acting determinants mediating the unconventional secretion of tau

Abstract The deposition of tau aggregates throughout the brain is a pathological characteristic within a group of neurodegenerative diseases collectively termed tauopathies, which includes Alzheimer’s disease. While recent findings suggest the involvement of unconventional secretory pathways driving...

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Bibliographic Details
Main Authors: Taxiarchis Katsinelos, William A. McEwan, Thomas R. Jahn, Walter Nickel
Format: Article
Language:English
Published: Nature Publishing Group 2021-06-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-021-92433-3