Contribution of O-GlcNAc modification of NF-κB p65 in the attenuation of diabetes-induced haptoglobin expression in rat liver

Contribution of O-GlcNAc modification of NF-κB p65 in the attenuation of diabetes-induced haptoglobin expression in rat liver

Haptoglobin (Hp) is a hemoglobin-binding protein that prevents free hemoglobin-induced tissue oxidative damage. In streptozotocin-induced diabetic rats, the initial elevation of Hp expression in the serum and liver tends to decrease with diabetes progression, contributing to increased oxidative stre...

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Bibliographic Details
Main Authors: Martinović Vesna I., Arambašić-Jovanović Jelena D., Bogojević Desanka B., Ivanović Anđelija S., Otašević Vesna M., Stančić Ana T., Grigorov Ilijana I.
Format: Article
Language:English
Published: University of Belgrade, University of Novi Sad 2020-01-01
Series:Archives of Biological Sciences
Subjects:
haptoglobin
gene expression
diabetes
nf-kb p65
o-linked-n-acetylglucosamine modification
Online Access:http://www.doiserbia.nb.rs/img/doi/0354-4664/2020/0354-46642000049M.pdf

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http://www.doiserbia.nb.rs/img/doi/0354-4664/2020/0354-46642000049M.pdf

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