Effect of TTN Mutations on Immune Microenvironment and Efficacy of Immunotherapy in Lung Adenocarcinoma Patients

Effect of TTN Mutations on Immune Microenvironment and Efficacy of Immunotherapy in Lung Adenocarcinoma Patients

Immune checkpoint inhibitors (ICIs) effectively treat lung adenocarcinoma (LUAD) with fewer side effects. However, for LUAD patients, the lack of predictive markers for ICIs makes their clinical benefits less than ideal. Despite reports suggesting that a TTN (titin) mutation plays an important role...

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Bibliographic Details
Main Authors: Zhe Wang, Chunguang Wang, Shengcheng Lin, Xin Yu
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-08-01
Series:Frontiers in Oncology
Subjects:
TTN
lung adenocarcinoma
immune checkpoint inhibitors
tumor microenvironment
immunogenicity
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2021.725292/full

Internet

https://www.frontiersin.org/articles/10.3389/fonc.2021.725292/full

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