Haemophagocytic lymphohistiocytosis occurred during induction chemotherapy in an acute monocytic leukemia patient with FLT3-ITD and DNMT3A mutations

Haemophagocytic lymphohistiocytosis occurred during induction chemotherapy in an acute monocytic leukemia patient with FLT3-ITD and DNMT3A mutations

Abstract Background Haemophagocytic lymphohistiocytosis (HLH) is considered to be a large challenge for clinicians due to the variable overlaps of symptoms with other severe diseases and a high rate of mortality. Prompt diagnosis and treatment are crucial to avoid a fatal outcome. However, very limi...

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Bibliographic Details
Main Authors: Fei Li, Xiaojie Zhang, Yunyun Wang, Ailin Yang, Zhanglin Zhang, Weiping Tang, Nan Zhong, Huidong Shi
Format: Article
Language:English
Published: BMC 2018-05-01
Series:BMC Cancer
Subjects:
Haemophagocytic lymphohistiocytosis
Malignancy
Acute monocytic leukemia
FLT3-ITD
DNMT3A
Online Access:http://link.springer.com/article/10.1186/s12885-018-4534-z

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http://link.springer.com/article/10.1186/s12885-018-4534-z

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