Rapid Assembly of Presynaptic Materials behind the Growth Cone in Dopaminergic Neurons Is Mediated by Precise Regulation of Axonal Transport

Summary: The proper assembly of neural circuits depends on the process of synaptogenesis, or the formation of synapses between partner neurons. Using the dopaminergic PDE neurons in C. elegans, we developed an in vivo system to study the earliest steps of the formation of en passant presynaptic spec...

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Bibliographic Details
Main Authors: David M. Lipton, Celine I. Maeder, Kang Shen
Format: Article
Language:English
Published: Elsevier 2018-09-01
Series:Cell Reports
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124718312294