Intracellular interleukin-32γ mediates antiviral activity of cytokines against hepatitis B virus

Intracellular interleukin-32γ mediates antiviral activity of cytokines against hepatitis B virus

Cytokines such as TNF and IFN-γ are important for immunity against hepatitis B virus (HBV). Here the authors show that interleukin-32 gamma (IL-32γ) acts downstream of TNF and IFN-γ as an intracellular effector, and that IL-32γ negatively regulates host factors contributing to HBV transcription to p...

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Bibliographic Details
Main Authors: Doo Hyun Kim, Eun-Sook Park, Ah Ram Lee, Soree Park, Yong Kwang Park, Sung Hyun Ahn, Hong Seok Kang, Ju Hee Won, Yea Na Ha, ByeongJune Jae, Dong-Sik Kim, Woo-Chang Chung, Moon Jung Song, Kee-Hwan Kim, Seung Hwa Park, Soo-Hyun Kim, Kyun-Hwan Kim
Format: Article
Language:English
Published: Nature Publishing Group 2018-08-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-018-05782-5

Internet

https://doi.org/10.1038/s41467-018-05782-5

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