Development of a dosing-adjustment tool for fluoroquinolones in osteoarticular infections: The Fluo-pop study

Development of a dosing-adjustment tool for fluoroquinolones in osteoarticular infections: The Fluo-pop study

Fluoroquinolones efficacy depend on both the drug exposure and the level of drug resistance of the bacteria responsible for the infection. Specifically for the Staphylococcus species, which is the microorganism mainly involved in osteoarticular infections (OAI), in-vitro data reported that an AUC/MI...

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Bibliographic Details
Main Authors: Florian Lemaitre, Fabien Fily, Jean-Baptiste Foulquier, Matthieu Revest, Vincent Jullien, Antoine Petitcollin, Pierre Tattevin, Camille Tron, Jean-Louis Polard, Marie-Clémence Verdier, Emmanuelle Comets, Denis Huten, Cédric Arvieux, Eric Bellissant, Bruno Laviolle
Format: Article
Language:English
Published: Elsevier 2021-10-01
Series:Biomedicine & Pharmacotherapy
Subjects:
Ofloxacin
Pharmacokinetics
Bone infection
Joint infection
Modeling
Online Access:http://www.sciencedirect.com/science/article/pii/S0753332221008362

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http://www.sciencedirect.com/science/article/pii/S0753332221008362

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