Indirubin inhibits Wnt/β-catenin signal pathway via promoter demethylation of WIF-1

Indirubin inhibits Wnt/β-catenin signal pathway via promoter demethylation of WIF-1

Abstract Background Psoriasis is a common inflammatory skin disease. Abnormal proliferation of keratinocytes is one of the psoriatic histopathological features. Indirubin has an essential effect on the proliferation and activation of keratinocytes; however, in psoriasis, the specific mechanism of ac...

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Bibliographic Details
Main Authors: Shou Gang Liu, Guang Pu Luo, Yong Bin Qu, Yong Feng Chen
Format: Article
Language:English
Published: BMC 2020-08-01
Series:BMC Complementary Medicine and Therapies
Subjects:
Indirubin
Wif-1
DNMT1
Wnt signal pathway
Psoriasis
Online Access:http://link.springer.com/article/10.1186/s12906-020-03045-9

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http://link.springer.com/article/10.1186/s12906-020-03045-9

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