IL-1Β enriched monocytes mount massive IL-6 responses to common inflammatory triggers among chronically HIV-1 infected adults on stable anti-retroviral therapy at risk for cardiovascular disease.

IL-1Β enriched monocytes mount massive IL-6 responses to common inflammatory triggers among chronically HIV-1 infected adults on stable anti-retroviral therapy at risk for cardiovascular disease.

Chronic infection by HIV increases the risk of cardiovascular disease (CVD) despite effective antiretroviral therapy (ART). The mechanisms linking HIV to CVD have yet to be fully elucidated. High plasma levels of the pro-inflammatory cytokine IL-6, which may be triggered by IL-1β, is a biomarker of...

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Bibliographic Details
Main Authors: Emilie Jalbert, Timothy Q Crawford, Michelle L D'Antoni, Sheila M Keating, Philip J Norris, Beau K Nakamoto, Todd Seto, Nisha I Parikh, Cecilia M Shikuma, Lishomwa C Ndhlovu, Jason D Barbour
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3783392?pdf=render

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http://europepmc.org/articles/PMC3783392?pdf=render

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