TLR4-mediated autophagic impairment contributes to neuropathic pain in chronic constriction injury mice

TLR4-mediated autophagic impairment contributes to neuropathic pain in chronic constriction injury mice

Abstract Neuropathic pain is a complex, chronic pain state characterized by hyperalgesia, allodynia, and spontaneous pain. Accumulating evidence has indicated that the microglial Toll-like receptor 4 (TLR4) and autophagy are implicated in neurodegenerative diseases, but their relationship and role i...

Full description

Bibliographic Details
Main Authors: Yibo Piao, Do Hyeong Gwon, Dong-Wook Kang, Tae Woong Hwang, Nara Shin, Hyeok Hee Kwon, Hyo Jung Shin, Yuhua Yin, Jwa-Jin Kim, Jinpyo Hong, Hyun-Woo Kim, Yonghyun Kim, Sang Ryong Kim, Sang-Ha Oh, Dong Woon Kim
Format: Article
Language:English
Published: BMC 2018-02-01
Series:Molecular Brain
Subjects:
TLR4
Autophagy
Glia
Neuropathic pain
CCI
Online Access:http://link.springer.com/article/10.1186/s13041-018-0354-y

Internet

http://link.springer.com/article/10.1186/s13041-018-0354-y

Similar Items