Constitutive phosphorylation of interferon receptor A-associated signaling proteins in systemic lupus erythematosus.

Constitutive phosphorylation of interferon receptor A-associated signaling proteins in systemic lupus erythematosus.

Overexpression of type I interferon (IFN-I)-induced genes is a common feature of systemic lupus erythematosus (SLE) and its experimental models, but the participation of endogenous overproduction of IFN-I on it is not clear. To explore the possibility that abnormally increased IFN-I receptor (IFNAR)...

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Bibliographic Details
Main Authors: Gabriela Ramírez-Vélez, Francisco Medina, Luis Ramírez-Montaño, Abraham Zarazúa-Lozada, Ramiro Hernández, Luis Llorente, José Moreno
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3408474?pdf=render

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http://europepmc.org/articles/PMC3408474?pdf=render

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