Following Ribosome Footprints to Understand Translation at a Genome Wide Level

Protein translation is a key step in gene expression. The development of Ribosome Profiling has allowed the global analysis of this process at sub-codon resolution. In the last years the method has been applied to several models ranging from bacteria to mammalian cells yielding a surprising amount o...

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Bibliographic Details
Main Authors: Guillermo Eastman, Pablo Smircich, José R. Sotelo-Silveira
Format: Article
Language:English
Published: Elsevier 2018-01-01
Series:Computational and Structural Biotechnology Journal
Online Access:http://www.sciencedirect.com/science/article/pii/S2001037018300023