Hypoxia-Inducible Factor 1 Protects Hypoxic Astrocytes against Glutamate Toxicity

Stroke is a major neurological disorder characterized by an increase in the Glu (glutamate) concentration resulting in excitotoxicity and eventually cellular damage and death in the brain. HIF-1 (hypoxia-inducible factor-1), a transcription factor, plays an important protective role in promoting cel...

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Bibliographic Details
Main Authors: Yomna Badawi, Prabhu Ramamoorthy, glian Shi
Format: Article
Language:English
Published: SAGE Publishing 2012-04-01
Series:ASN Neuro
Online Access:https://doi.org/10.1042/AN20120006