Hypoxia-Inducible Factor 1 Protects Hypoxic Astrocytes against Glutamate Toxicity
Stroke is a major neurological disorder characterized by an increase in the Glu (glutamate) concentration resulting in excitotoxicity and eventually cellular damage and death in the brain. HIF-1 (hypoxia-inducible factor-1), a transcription factor, plays an important protective role in promoting cel...
Main Authors: | , , |
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Format: | Article |
Language: | English |
Published: |
SAGE Publishing
2012-04-01
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Series: | ASN Neuro |
Online Access: | https://doi.org/10.1042/AN20120006 |