A novel FLI1 exonic circular RNA promotes metastasis in breast cancer by coordinately regulating TET1 and DNMT1

A novel FLI1 exonic circular RNA promotes metastasis in breast cancer by coordinately regulating TET1 and DNMT1

Abstract Background Friend leukemia virus integration 1 (FLI1), an ETS transcription factor family member, acts as an oncogenic driver in hematological malignancies and promotes tumor growth in solid tumors. However, little is known about the mechanisms underlying the activation of this proto-oncoge...

Full description

Bibliographic Details
Main Authors: Naifei Chen, Gang Zhao, Xu Yan, Zheng Lv, Hongmei Yin, Shilin Zhang, Wei Song, Xueli Li, Lingyu Li, Zhonghua Du, Lin Jia, Lei Zhou, Wei Li, Andrew R. Hoffman, Ji-Fan Hu, Jiuwei Cui
Format: Article
Language:English
Published: BMC 2018-12-01
Series:Genome Biology
Subjects:
Circular RNA
FLI1
Breast cancer
DNA methylation
TET1
DNMT1
Online Access:http://link.springer.com/article/10.1186/s13059-018-1594-y

Internet

http://link.springer.com/article/10.1186/s13059-018-1594-y

Similar Items