Prediction of steps in the evolution of variola virus host range.

Variola virus, the agent of smallpox, has a severely restricted host range (humans) but a devastatingly high mortality rate. Although smallpox has been eradicated by a World Health Organization vaccination program, knowledge of the evolutionary processes by which human super-pathogens such as variol...

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Bibliographic Details
Main Authors: Chad Smithson, Alex Purdy, Adrian J Verster, Chris Upton
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3953476?pdf=render