MicroRNA 876-5p modulates EV-A71 replication through downregulation of host antiviral factors

Abstract Background Human enterovirus 71 (EV-A71) is a non-enveloped virus that has a single stranded positive sense RNA genome. In a previous study, we showed that miR-876-5p upregulation was observed in the serum of patients with severe EV-A71 infection. Micro-876-5p (miR-876-5p) is a circulating...

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Bibliographic Details
Main Authors: Peng Xu, Hwa Xu, Hsu Sheng Cheng, Han-Hsiang Chan, Robert Y. L. Wang
Format: Article
Language:English
Published: BMC 2020-02-01
Series:Virology Journal
Subjects:
Online Access:https://doi.org/10.1186/s12985-020-1284-8