pH-Responsive Nanostructures Based on Surface Active Fatty Acid-Protic Ionic Liquids for Imiquimod Delivery in Skin Cancer Topical Therapy

pH-Responsive Nanostructures Based on Surface Active Fatty Acid-Protic Ionic Liquids for Imiquimod Delivery in Skin Cancer Topical Therapy

For topical treatment of skin cancer, the design of pH-responsive nanocarriers able to selectively release the drug in the tumor acidic microenvironment represents a reliable option for targeted delivery. In this context, a series of newly synthesized surface-active fatty acid-protic ionic liquids (...

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Bibliographic Details
Main Authors: Silvia Tampucci, Lorenzo Guazzelli, Susi Burgalassi, Sara Carpi, Patrizia Chetoni, Andrea Mezzetta, Paola Nieri, Beatrice Polini, Christian Silvio Pomelli, Eleonora Terreni, Daniela Monti
Format: Article
Language:English
Published: MDPI AG 2020-11-01
Series:Pharmaceutics
Subjects:
ionic liquids
nanostructures
imiquimod
skin cancer
topical drug delivery
Online Access:https://www.mdpi.com/1999-4923/12/11/1078

Internet

https://www.mdpi.com/1999-4923/12/11/1078

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