Probing the Effective Treatment Thresholds for Alteplase in Acute Ischemic Stroke With Regression Discontinuity Designs

Probing the Effective Treatment Thresholds for Alteplase in Acute Ischemic Stroke With Regression Discontinuity Designs

Randomized Controlled Trials (RCTs) are considered the gold standard for measuring the efficacy of medical interventions. However, RCTs are expensive, and use a limited population. Techniques to estimate the effects of stroke interventions from observational data that minimize confounding would be u...

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Bibliographic Details
Main Authors: Andrew M. Naidech, Patrick N. Lawlor, Haolin Xu, Gregg C. Fonarow, Ying Xian, Eric E. Smith, Lee Schwamm, Roland Matsouaka, Shyam Prabhakaran, Ioana Marinescu, Konrad P. Kording
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-09-01
Series:Frontiers in Neurology
Subjects:
alteplase
ischemic stroke
regression discontinuity design
causal inference
quasi-experiments
Online Access:https://www.frontiersin.org/article/10.3389/fneur.2020.00961/full

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https://www.frontiersin.org/article/10.3389/fneur.2020.00961/full

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