Incidentally identified genetic variants in arrhythmogenic right ventricular cardiomyopathy‐associated genes among children undergoing exome sequencing reflect healthy population variation

Incidentally identified genetic variants in arrhythmogenic right ventricular cardiomyopathy‐associated genes among children undergoing exome sequencing reflect healthy population variation

Abstract Background With expanding use of clinical whole exome sequencing (WES), genetic variants of uncertain significance are increasingly identified. As pathologic mutations in genes associated with arrhythmogenic right ventricular cardiomyopathy (ARVC) carry a risk of sudden death, determining t...

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Bibliographic Details
Main Authors: Andrew T. Headrick, Jill A. Rosenfeld, Yaping Yang, Hari Tunuguntla, Hugh D. Allen, Daniel J. Penny, Jeffrey J. Kim, Andrew P. Landstrom
Format: Article
Language:English
Published: Wiley 2019-06-01
Series:Molecular Genetics & Genomic Medicine
Subjects:
arrhythmogenic right ventricular cardiomyopathy
genetic testing
genetics
incidental finding
secondary finding
variant of undetermined significance
Online Access:https://doi.org/10.1002/mgg3.593

Internet

https://doi.org/10.1002/mgg3.593

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