Generation of a nanobody targeting the paraflagellar rod protein of trypanosomes.

Trypanosomes are protozoan parasites that cause diseases in humans and livestock for which no vaccines are available. Disease eradication requires sensitive diagnostic tools and efficient treatment strategies. Immunodiagnostics based on antigen detection are preferable to antibody detection because...

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Bibliographic Details
Main Authors: Emmanuel Obishakin, Benoit Stijlemans, Julien Santi-Rocca, Isabel Vandenberghe, Bart Devreese, Serge Muldermans, Philippe Bastin, Stefan Magez
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0115893