Human iPSC-derived chondrocytes mimic juvenile chondrocyte function for the dual advantage of increased proliferation and resistance to IL-1β

Human iPSC-derived chondrocytes mimic juvenile chondrocyte function for the dual advantage of increased proliferation and resistance to IL-1β

Abstract Background Induced pluripotent stem cells (iPSC) provide an unlimited patient-specific cell source for regenerative medicine. Adult cells have had limited success in cartilage repair, but juvenile chondrocytes (from donors younger than 13 years of age) have been identified to generate super...

Full description

Bibliographic Details
Main Authors: Jieun Lee, Piera Smeriglio, Constance R. Chu, Nidhi Bhutani
Format: Article
Language:English
Published: BMC 2017-11-01
Series:Stem Cell Research & Therapy
Subjects:
Human iPSC-derived chondrocytes
Cartilage
Inflammation
Juvenile chondrocytes
CD24
Online Access:http://link.springer.com/article/10.1186/s13287-017-0696-x

Internet

http://link.springer.com/article/10.1186/s13287-017-0696-x

Similar Items