Human Lymph Node Stromal Cells Have the Machinery to Regulate Peripheral Tolerance during Health and Rheumatoid Arthritis

Human Lymph Node Stromal Cells Have the Machinery to Regulate Peripheral Tolerance during Health and Rheumatoid Arthritis

<b>A</b><b>bstract:</b> Background: In rheumatoid arthritis (RA) the cause for loss of tolerance and anti-citrullinated protein antibody (ACPA) production remains unidentified. Mouse studies showed that lymph node stromal cells (LNSCs) maintain peripheral tolerance through pr...

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Bibliographic Details
Main Authors: Janine S. Hähnlein, Reza Nadafi, Tineke A. de Jong, Johanna F. Semmelink, Ester B. M. Remmerswaal, Mary Safy, Krijn P. van Lienden, Mario Maas, Danielle M. Gerlag, Paul P. Tak, Reina E. Mebius, Heidi Wähämaa, Anca I. Catrina, Lisa G. M. van Baarsen
Format: Article
Language:English
Published: MDPI AG 2020-08-01
Series:International Journal of Molecular Sciences
Subjects:
lymph node stromal cells
rheumatoid arthritis
tolerance
autoimmunity
Online Access:https://www.mdpi.com/1422-0067/21/16/5713

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https://www.mdpi.com/1422-0067/21/16/5713

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