Severe Acute Respiratory Syndrome Coronavirus 2 Spike Protein Based Novel Epitopes Induce Potent Immune Responses in vivo and Inhibit Viral Replication in vitro

Severe Acute Respiratory Syndrome Coronavirus 2 Spike Protein Based Novel Epitopes Induce Potent Immune Responses in vivo and Inhibit Viral Replication in vitro

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) initiates infection by attachment of the surface-exposed spike glycoprotein to the host cell receptors. The spike glycoprotein (S) is a promising target for inducing immune responses and providing protection; thus the ongoing efforts for t...

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Bibliographic Details
Main Authors: Preeti Vishwakarma, Naveen Yadav, Zaigham Abbas Rizvi, Naseem Ahmed Khan, Adarsh Kumar Chiranjivi, Shailendra Mani, Manish Bansal, Prabhanjan Dwivedi, Tripti Shrivastava, Rajesh Kumar, Amit Awasthi, Shubbir Ahmed, Sweety Samal
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-03-01
Series:Frontiers in Immunology
Subjects:
spike (S) glycoprotein
peptide
vaccine
antiviral activity
immune response
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2021.613045/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2021.613045/full

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