Gene expression dysregulation domains are not a specific feature of Down syndrome
Gene expression dysregulation domains (GEDDs) have been reported in Down syndrome (DS) cells, where changes in gene expression are clustered. Here the authors find that, while GEDDs are present in DS cells and in the Dp1Tyb mouse model of DS, GEDDs do not depend on the DS genotype and occur whenever...
| Main Authors: | , , , , , , , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Nature Publishing Group
2019-06-01
|
| Series: | Nature Communications |
| Online Access: | https://doi.org/10.1038/s41467-019-10129-9 |