Constitutive activation of kappa opioid receptors at ventral tegmental area inhibitory synapses following acute stress

Constitutive activation of kappa opioid receptors at ventral tegmental area inhibitory synapses following acute stress

Stressful experiences potently activate kappa opioid receptors (κORs). κORs in the ventral tegmental area regulate multiple aspects of dopaminergic and non-dopaminergic cell function. Here we show that at GABAergic synapses on rat VTA dopamine neurons, a single exposure to a brief cold-water swim st...

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Bibliographic Details
Main Authors: Abigail M Polter, Kelsey Barcomb, Rudy W Chen, Paige M Dingess, Nicholas M Graziane, Travis E Brown, Julie A Kauer
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2017-04-01
Series:eLife
Subjects:
VTA
Synaptic Plasticity
GABA
Kappa Opioid Receptor
Stress
dopamine
Online Access:https://elifesciences.org/articles/23785

Internet

https://elifesciences.org/articles/23785

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