Sublingual Immunization With an RSV G Glycoprotein Fragment Primes IL-17-Mediated Immunopathology Upon Respiratory Syncytial Virus Infection

Sublingual Immunization With an RSV G Glycoprotein Fragment Primes IL-17-Mediated Immunopathology Upon Respiratory Syncytial Virus Infection

Respiratory syncytial virus (RSV) is the leading cause of serious respiratory tract disease but there is no licensed RSV vaccine. Immunopathological mechanisms have long been suspected as operating in the development of severe RSV disease and have hampered the development of safe and effective vacci...

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Bibliographic Details
Main Authors: In Su Cheon, Joo Young Kim, Youngjoo Choi, Byoung-Shik Shim, Jung-ah Choi, Dae-Im Jung, Jae-Ouk Kim, Thomas J. Braciale, Hyewon Youn, Man Ki Song, Jun Chang
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-03-01
Series:Frontiers in Immunology
Subjects:
RSV
glycoprotein
sublingual
IL-17
immunopathology
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2019.00567/full

Internet

https://www.frontiersin.org/article/10.3389/fimmu.2019.00567/full

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