Generation of functional neuromuscular junctions from human pluripotent stem cell lines

Generation of functional neuromuscular junctions from human pluripotent stem cell lines

Several neuromuscular diseases involve dysfunction of neuromuscular junctions (NMJs), yet there are no patient-specific human models for electrophysiological characterization of NMJ. We seeded cells of neurally-induced embryoid body-like spheres derived from induced pluripotent stem cell (iPSC) or e...

Full description

Bibliographic Details
Main Authors: Katja ePuttonen, Marika eRuponen, Nikolay eNaumenko, Outi Hovatta Hovatta, Pasi eTavi, Jari eKoistinaho
Format: Article
Language:English
Published: Frontiers Media S.A. 2015-12-01
Series:Frontiers in Cellular Neuroscience
Subjects:
cell culture
human
skeletal muscle
embryonic
induced pluripotent stem cell
Nerve Cell Engineering
Online Access:http://journal.frontiersin.org/Journal/10.3389/fncel.2015.00473/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fncel.2015.00473/full

Similar Items