Musclin, A Myokine Induced by Aerobic Exercise, Retards Muscle Atrophy During Cancer Cachexia in Mice

Musclin, A Myokine Induced by Aerobic Exercise, Retards Muscle Atrophy During Cancer Cachexia in Mice

Physical activity improves the prognosis of cancer patients, partly by contrasting the associated muscle wasting (cachexia), through still unknown mechanisms. We asked whether aerobic exercise causes secretion by skeletal muscles of proteins (myokines) that may contrast cachexia. Media conditioned b...

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Bibliographic Details
Main Authors: Andrea D. Re Cecconi, Mara Forti, Michela Chiappa, Zhiyong Zhu, Leonid V. Zingman, Luigi Cervo, Luca Beltrame, Sergio Marchini, Rosanna Piccirillo
Format: Article
Language:English
Published: MDPI AG 2019-10-01
Series:Cancers
Subjects:
muscle wasting
muscle atrophy
aerobic exercise
cancer cachexia
myokine
musclin
pgc1α
Online Access:https://www.mdpi.com/2072-6694/11/10/1541

Internet

https://www.mdpi.com/2072-6694/11/10/1541

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