Efficient metabolic evolution of engineered Yarrowia lipolytica for succinic acid production using a glucose-based medium in an in situ fibrous bioreactor under low-pH condition

Efficient metabolic evolution of engineered Yarrowia lipolytica for succinic acid production using a glucose-based medium in an in situ fibrous bioreactor under low-pH condition

Abstract Background Alkali used for pH control during fermentation and acidification for downstream recovery of succinic acid (SA) are the two largest cost contributors for bio-based SA production. To promote the commercialization process of fermentative SA, the development of industrially important...

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Bibliographic Details
Main Authors: Chong Li, Shi Gao, Xiaotong Li, Xiaofeng Yang, Carol Sze Ki Lin
Format: Article
Language:English
Published: BMC 2018-08-01
Series:Biotechnology for Biofuels
Subjects:
Metabolic evolution
Succinic acid
Yarrowia lipolytica
In-situ fibrous bed bioreactor
Online Access:http://link.springer.com/article/10.1186/s13068-018-1233-6

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http://link.springer.com/article/10.1186/s13068-018-1233-6

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