Mechanism of piR-DQ590027/MIR17HG regulating the permeability of glioma conditioned normal BBB

Abstract Background The blood-brain barrier (BBB) strongly restricts the entry of anti-glioma drugs into tumor tissues and thus decreases chemotherapy efficacy. Malignant gliomas are highly invasive tumours that use the perivascular space for invasion and co-opt existing vessels as satellite tumor f...

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Bibliographic Details
Main Authors: Xue Leng, Jun Ma, Yunhui Liu, Shuyuan Shen, Hai Yu, Jian Zheng, Xiaobai Liu, Libo Liu, Jiajia Chen, Lini Zhao, Xuelei Ruan, Yixue Xue
Format: Article
Language:English
Published: BMC 2018-10-01
Series:Journal of Experimental & Clinical Cancer Research
Subjects:
Online Access:http://link.springer.com/article/10.1186/s13046-018-0886-0