Direct recognition of Fusobacterium nucleatum by the NK cell natural cytotoxicity receptor NKp46 aggravates periodontal disease.

Periodontitis is a common human chronic inflammatory disease that results in the destruction of the tooth attachment apparatus and tooth loss. Although infections with periopathogenic bacteria such as Porphyromonas gingivalis (P. gingivalis) and Fusobacterium nucleatum (F. nucleatum) are essential f...

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Bibliographic Details
Main Authors: Stella Chaushu, Asaf Wilensky, Chamutal Gur, Lior Shapira, Moran Elboim, Gili Halftek, David Polak, Hagit Achdout, Gilad Bachrach, Ofer Mandelboim
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS Pathogens
Online Access:http://europepmc.org/articles/PMC3310798?pdf=render