In-vivo quantitative proteomics reveals a key contribution of post-transcriptional mechanisms to the circadian regulation of liver metabolism.

Circadian clocks are endogenous oscillators that drive the rhythmic expression of a broad array of genes, orchestrating metabolism and physiology. Recent evidence indicates that post-transcriptional and post-translational mechanisms play essential roles in modulating temporal gene expression for pro...

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Bibliographic Details
Main Authors: Maria S Robles, Jürgen Cox, Matthias Mann
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS Genetics
Online Access:http://europepmc.org/articles/PMC3879213?pdf=render