Conservation and immunogenicity of novel antigens in diverse isolates of enterotoxigenic Escherichia coli.

BACKGROUND:Enterotoxigenic Escherichia coli (ETEC) are common causes of diarrheal morbidity and mortality in developing countries for which there is currently no vaccine. Heterogeneity in classical ETEC antigens known as colonization factors (CFs) and poor efficacy of toxoid-based approaches to date...

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Bibliographic Details
Main Authors: Qingwei Luo, Firdausi Qadri, Rita Kansal, David A Rasko, Alaullah Sheikh, James M Fleckenstein
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS Neglected Tropical Diseases
Online Access:http://europepmc.org/articles/PMC4309559?pdf=render