Shift towards pro-inflammatory intestinal bacteria aggravates acute murine colitis via Toll-like receptors 2 and 4.

Shift towards pro-inflammatory intestinal bacteria aggravates acute murine colitis via Toll-like receptors 2 and 4.

<h4>Background</h4>Gut bacteria trigger colitis in animal models and are suspected to aggravate inflammatory bowel diseases. We have recently reported that Escherichia coli accumulates in murine ileitis and exacerbates small intestinal inflammation via Toll-like receptor (TLR) signaling....

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Main Authors: Markus M Heimesaat, André Fischer, Britta Siegmund, Andreas Kupz, Julia Niebergall, David Fuchs, Hannah-Katharina Jahn, Marina Freudenberg, Christoph Loddenkemper, Arvind Batra, Hans-Anton Lehr, Oliver Liesenfeld, Michael Blaut, Ulf B Göbel, Ralf R Schumann, Stefan Bereswill
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2007-07-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0000662

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https://doi.org/10.1371/journal.pone.0000662

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