Computing Ka and Ks with a consideration of unequal transitional substitutions

<p>Abstract</p> <p>Background</p> <p>Approximate methods for estimating nonsynonymous and synonymous substitution rates (Ka and Ks) among protein-coding sequences have adopted different mutation (substitution) models. In the past two decades, several methods have been p...

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Bibliographic Details
Main Authors: Zhang Zhang, Li Jun, Yu Jun
Format: Article
Language:English
Published: BMC 2006-06-01
Series:BMC Evolutionary Biology
Online Access:http://www.biomedcentral.com/1471-2148/6/44