Role of C5 inhibition in Idiopathic Inflammatory Myopathies and Scleroderma Renal Crisis–Induced Thrombotic Microangiopathies

Role of C5 inhibition in Idiopathic Inflammatory Myopathies and Scleroderma Renal Crisis–Induced Thrombotic Microangiopathies

Introduction: Connective tissue diseases, including systemic sclerosis and idiopathic inflammatory myopathies (IIMs), are a very rare cause of thrombotic microangiopathies (TMAs). Whether dysregulation of the complement pathways underlies these secondary forms of TMA and may be targeted by complemen...

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Bibliographic Details
Main Authors: Anna Gouin, David Ribes, Magali Colombat, Dominique Chauveau, Gregoire Prevot, Olivier Lairez, Gregory Pugnet, Veronique Fremeaux-Bacchi, Antoine Huart, Julie Belliere, Stanislas Faguer
Format: Article
Language:English
Published: Elsevier 2021-04-01
Series:Kidney International Reports
Subjects:
C5 blocking
connective disease
C5b9
thrombotic microangiopathy
Online Access:http://www.sciencedirect.com/science/article/pii/S2468024921000243

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http://www.sciencedirect.com/science/article/pii/S2468024921000243

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