Bisphenol A Inhibits the Transporter Function of the Blood-Brain Barrier by Directly Interacting with the ABC Transporter Breast Cancer Resistance Protein (BCRP)

The breast cancer resistance protein (BCRP) is an important efflux transporter in the blood-brain barrier (BBB), protecting the brain from a wide range of substances. In this study, we investigated if BCRP function is affected by bisphenol A (BPA), a high production volume chemical used in common co...

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Bibliographic Details
Main Authors: Elin Engdahl, Maarten D. M. van Schijndel, Dimitrios Voulgaris, Michela Di Criscio, Kerry A. Ramsbottom, Daniel J. Rigden, Anna Herland, Joëlle Rüegg
Format: Article
Language:English
Published: MDPI AG 2021-05-01
Series:International Journal of Molecular Sciences
Subjects:
BPA
BPF
BPS
BBB
Online Access:https://www.mdpi.com/1422-0067/22/11/5534