Orexin - does it have a role in mental illness?

Orexin-A and Orexin-B (also known as hypocretin 1 and 2) are, respectively, 33- and 28-amino acid residue peptides that activate a G-protein-coupled ‘orphan’ receptor, i.e. which has no known ligand.  Immuno-cytochemical studies show that orexin-positive neurons are located in the lateral hypothalam...

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Bibliographic Details
Main Authors: M Y H Moosa, F Y Jeenah
Format: Article
Language:English
Published: AOSIS 2008-06-01
Series:South African Journal of Psychiatry
Online Access:http://www.sajp.org.za/index.php/sajp/article/view/159