Spontaneous development of neoplasms in severe combined immunodeficient mice

Severe combined immunodeficient (SCID) mice lack functional T and B cells. This renders them useful for implantation of human cells. The absence of immune cells, however, makes severe combined immunodeficient mice highly susceptible to infections and spontaneous development of malignancies; 2 of 114...

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Bibliographic Details
Main Author: Rekha Samuel
Format: Article
Language:English
Published: SAGE Publishing 2015-01-01
Series:SAGE Open Medical Case Reports
Online Access:https://doi.org/10.1177/2050313X14568698