Review: Efficacy and safety of adalimumab in Crohn's disease

Adalimumab (ADA) is a subcutaneously (SC) self-administered fully human Ig G1 monoclonal antibody directed against tumor necrosis factor alpha (TNFα). In the CLASSIC I dose-ranging trial, ADA was superior to placebo for inducing remission in patients with moderate-to-severe Crohn's disease (CD)...

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Bibliographic Details
Main Authors: Gary R. Lichtenstein, Remo Panaccione, Gordon Mallarkey
Format: Article
Language:English
Published: SAGE Publishing 2008-07-01
Series:Therapeutic Advances in Gastroenterology
Online Access:https://doi.org/10.1177/1756283X08092548