Targeting Signal 3 Extracellularly and Intracellularly in Graft-Versus-Host Disease

Targeting Signal 3 Extracellularly and Intracellularly in Graft-Versus-Host Disease

Allogeneic hematopoietic stem cell transplantation (allo-HCT) holds curative potential for many hematological disorders. However, the pathophysiology of the desired graft-versus-tumor effect is linked to life-threatening complications of acute graft-versus-host disease (GVHD). Allogeneic donor T lym...

Full description

Bibliographic Details
Main Authors: Stephanie Kim, Pavan Reddy
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-04-01
Series:Frontiers in Immunology
Subjects:
bone marrow transplantation
graft-versus-host disease
cytokines
alloimmunity
intracellular trafficking
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2020.00722/full

Internet

https://www.frontiersin.org/article/10.3389/fimmu.2020.00722/full

Similar Items