Immunogenic-cell-killing and immunosuppression-inhibiting nanomedicine

Immunogenic-cell-killing and immunosuppression-inhibiting nanomedicine

Combining chemo-therapeutics with immune checkpoint inhibitors facilitates killing cancer cells and activating the immune system through inhibiting immune escape. However, their treatment effects remain limited due to the compromised accumulation of both drugs and inhibitors in certain tumor tissues...

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Bibliographic Details
Main Authors: Ying Wang, Di Gao, Yan Liu, Xiaoqing Guo, Shuojia Chen, Li Zeng, Jinxuan Ma, Xingcai Zhang, Zhongmin Tian, Zhe Yang
Format: Article
Language:English
Published: KeAi Communications Co., Ltd. 2021-06-01
Series:Bioactive Materials
Subjects:
Controllable upper critical solution temperature (UCST)
Immunogenic cell death (ICD)
Indoleamine 2,3-dioxygenase 1 (IDO1)
Drug delivery
Cancer chemoimmunotherapy
Online Access:http://www.sciencedirect.com/science/article/pii/S2452199X20303005

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http://www.sciencedirect.com/science/article/pii/S2452199X20303005

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