A ChIP on the shoulder? Chromatin immunoprecipitation and validation strategies for ChIP antibodies [version 1; referees: 2 approved]

Chromatin immunoprecipitation (ChIP) is a technique widely used in the study of epigenetics and transcriptional regulation of gene expression. However, its antibody-centric nature exposes it to similar challenges faced by other antibody-based procedures, of which the most prominent are issues of spe...

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Bibliographic Details
Main Authors: Fiona C. Wardle, Haihan Tan
Format: Article
Language:English
Published: F1000 Research Ltd 2015-07-01
Series:F1000Research
Subjects:
Online Access:http://f1000research.com/articles/4-235/v1