Sensitive bioluminescence imaging of fungal dissemination to the brain in mouse models of cryptococcosis

Sensitive bioluminescence imaging of fungal dissemination to the brain in mouse models of cryptococcosis

Cryptococcus neoformans is a leading cause of fungal brain infection, but the mechanism of dissemination and dynamics of cerebral infection following pulmonary disease are poorly understood. To address these questions, non-invasive techniques that can study the dynamic processes of disease developme...

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Bibliographic Details
Main Authors: Liesbeth Vanherp, Alexandra Ristani, Jennifer Poelmans, Amy Hillen, Katrien Lagrou, Guilhem Janbon, Matthias Brock, Uwe Himmelreich, Greetje Vande Velde
Format: Article
Language:English
Published: The Company of Biologists 2019-06-01
Series:Disease Models & Mechanisms
Subjects:
Cryptococcus
Pulmonary disease
Mouse model
Fungal infection
Blood-brain barrier
Non-invasive imaging
Online Access:http://dmm.biologists.org/content/12/6/dmm039123

Internet

http://dmm.biologists.org/content/12/6/dmm039123

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