Potential of miR-21 to Predict Incomplete Response to Chemoradiotherapy in Rectal Adenocarcinoma

Potential of miR-21 to Predict Incomplete Response to Chemoradiotherapy in Rectal Adenocarcinoma

Background: Patients with locally advanced rectal adenocarcinoma (LARC) are treated with neoadjuvant chemoradiotherapy (CRT). However, biomarkers for patient selection are lacking, and the association between miRNA expression and treatment response and oncological outcomes is unclear.Objectives: To...

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Bibliographic Details
Main Authors: Susana Ourô, Cláudia Mourato, Sónia Velho, André Cardador, Marisa P. Ferreira, Diogo Albergaria, Rui E. Castro, Rui Maio, Cecília M. P. Rodrigues
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-10-01
Series:Frontiers in Oncology
Subjects:
rectal cancer
chemoradiotherapy response
tumor regression grade
miR-21
biomarkers
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2020.577653/full

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https://www.frontiersin.org/articles/10.3389/fonc.2020.577653/full

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