Nicotine enhances murine airway contractile responses to kinin receptor agonists via activation of JNK- and PDE4-related intracellular pathways

<p>Abstract</p> <p>Background</p> <p>Nicotine plays an important role in cigarette-smoke-associated airway disease. The present study was designed to examine if nicotine could induce airway hyperresponsiveness through kinin receptors, and if so, explore the underlying m...

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Bibliographic Details
Main Authors: Cardell Lars-Olaf, Zhang Yaping, Xu Yuan
Format: Article
Language:English
Published: BMC 2010-01-01
Series:Respiratory Research
Online Access:http://respiratory-research.com/content/11/1/13