Lipoprotein (a) upregulates ABCA1 in liver cells via scavenger receptor-B1 through its oxidized phospholipids[S]

Lipoprotein (a) upregulates ABCA1 in liver cells via scavenger receptor-B1 through its oxidized phospholipids[S]

Elevated levels of lipoprotein (a) [Lp(a)] are a well-established risk factor for developing CVD. While Lp(a) levels are thought to be independent of other plasma lipoproteins, some trials have reported a positive association between Lp(a) and HDL. Whether Lp(a) has a direct effect on HDL is not kno...

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Bibliographic Details
Main Authors: Monika Sharma, Anne Von Zychlinski-Kleffmann, Carolyn M. Porteous, Gregory T. Jones, Michael J.A. Williams, Sally P.A. McCormick
Format: Article
Language:English
Published: Elsevier 2015-07-01
Series:Journal of Lipid Research
Subjects:
adenosine 5′-triphosphate binding cassette transporter A1
cholesterol efflux
high density lipoprotein
nuclear receptor/liver X receptor
nuclear receptor/peroxisome proliferator-activated receptor
Online Access:http://www.sciencedirect.com/science/article/pii/S0022227520355516

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http://www.sciencedirect.com/science/article/pii/S0022227520355516

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